About Duphaston Tablet
Duphaston Tablet contains Dydrogesterone 10 mg. Dydrogesterone is a man-made hormone similar to progesterone, a natural female hormone. It is used for several conditions linked to low progesterone, such as irregular or painful periods, endometriosis and some pregnancy-related problems. It is also used with oestrogen in hormone replacement therapy. It is not a contraceptive.
Uses of Duphaston Tablet
- Irregular, heavy or painful periods caused by hormone imbalance
- Endometriosis
- Threatened or repeated miscarriage linked to low progesterone, as advised by a doctor
- Support for the womb lining during fertility treatment
- Protecting the womb lining in hormone replacement therapy, together with oestrogen
Benefits
In period problems and endometriosis
It helps regulate the womb lining, which can make periods more regular and reduce pain and heavy bleeding.
In pregnancy support and fertility treatment
It supports the womb lining where low progesterone is thought to be a factor. Your doctor will decide if it is suitable.
Side effects
Most side effects are mild. Tell your doctor about any unexpected or heavy bleeding.
Common
- Headache or migraine
- Nausea
- Breast tenderness
- Irregular bleeding or spotting
- Bloating
Get medical help if you notice
- Yellowing of the skin or eyes, or severe tummy pain (possible liver problem) — contact your doctor
- Severe or lasting low mood — contact your doctor
- Allergic reaction: rash, swelling of the face or lips, difficulty breathing — seek emergency care
- If used with oestrogen: pain or swelling in one leg, sudden chest pain or breathlessness — seek emergency care
How to use
Take it exactly as your doctor prescribed. Depending on your condition, you may take it on certain days of your cycle or every day. Swallow the tablet with water, with or without food.
How it works
It acts on progesterone receptors in the womb. This helps prepare and maintain the womb lining and supports a regular cycle.
Safety advice
Alcohol Caution
No interaction is known, but it is best to limit alcohol, especially if you are pregnant or trying to conceive.
Pregnancy Consult your doctor
It is sometimes prescribed in early pregnancy for specific reasons. Use it only as your doctor advises.
Breastfeeding Unsafe
Labelling advises it should not be used while breastfeeding.
Driving Caution
It may occasionally cause mild dizziness or sleepiness. Do not drive if you feel affected.
Kidney Consult your doctor
Limited information is available. Tell your doctor if you have kidney disease.
Liver Caution
Tell your doctor if you have or have had liver disease; it may not be suitable.
If you miss a dose
If you miss a dose, take it as soon as you remember. If it is nearly time for the next dose, skip the missed one. Do not take two doses together. Tell your doctor, as missed doses may cause spotting.
Quick tips
- It is not a contraceptive; use other contraception if needed.
- Take it on the exact days your doctor has told you.
- Tell your doctor about any unexpected bleeding.
- Tell your doctor if you have had a meningioma, liver disease or depression.
Substitutes
Same salts in the same strength from other makers. Only switch brands on your doctor's or pharmacist's advice; our pharmacist checks every order against the prescription.
Fact box
- Chemical class
- Retroprogesterone
- Therapeutic class
- Hormones / gynaecological
- Action class
- Progestogen
- Habit forming
- No
- Prescription
- Required
Interactions with other medicines
Tell your doctor and pharmacist about every medicine, vitamin and herbal product you take.
| Medicine | What can happen |
|---|---|
| Rifampicin, carbamazepine, phenytoin and phenobarbital | Can speed up the breakdown of dydrogesterone and reduce its effect |
| St John's wort (herbal remedy) | May reduce its effect |
This page is general information to help you understand your medicine. It is not a substitute for advice from your doctor or pharmacist. Do not start, stop or change a medicine on your own.
Written by the Asthra Health Care team from the approved prescribing information (Dydrogesterone prescribing information (CDSCO-approved labelling); Dydrogesterone Summary of Product Characteristics). Pharmacist review pending.