About Zerodol-SP Tablet
Zerodol-SP Tablet contains Aceclofenac 100 mg + Paracetamol 325 mg + Serratiopeptidase 15 mg. This combination is used to relieve pain and swelling, for example after an injury, dental work, surgery or in joint and muscle conditions. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID), paracetamol is a pain and fever reliever, and serratiopeptidase is an enzyme. It is usually taken after food for a short time.
Uses of Zerodol-SP Tablet
- Pain and swelling after injury, surgery or dental procedures
- Joint and muscle pain
- Pain and swelling in conditions such as osteoarthritis and rheumatoid arthritis
Benefits
In pain and swelling
It helps ease pain and reduce swelling and stiffness, which can make it easier to move and carry on with daily activities. It is meant for short-term use as advised by your doctor.
Side effects
Most side effects are mild and settle as your body gets used to the medicine. Talk to your doctor if any of them bother you or do not go away.
Common
- Nausea
- Indigestion or heartburn
- Stomach pain
- Diarrhoea
- Dizziness
Get medical help if you notice
- Signs of bleeding in the stomach or gut: black or tarry stools, vomiting blood or material that looks like coffee grounds, or severe stomach pain — stop and get medical help straight away
- Reduced urine, swelling of the legs or feet — may be a sign of kidney problems; contact your doctor
- Chest pain, sudden weakness on one side or trouble speaking — seek emergency care
- Yellowing of the skin or eyes or dark urine — contact a doctor straight away
- Allergic reaction: rash, itching, swelling of the face, lips or throat, or difficulty breathing — seek emergency care
How to use
Take it exactly as your doctor prescribed, usually after food to reduce stomach upset. Swallow the tablet whole with water. Use it for the shortest time your doctor advises.
How it works
Aceclofenac blocks chemicals called prostaglandins that cause pain and swelling. Paracetamol adds pain and fever relief by acting in the brain. Serratiopeptidase is an enzyme that is used with the aim of reducing swelling.
Safety advice
Alcohol Unsafe
Avoid alcohol. It increases the risk of stomach bleeding and liver harm.
Pregnancy Unsafe
Not recommended in pregnancy and must not be used in the last 3 months, as NSAIDs can harm the baby. Talk to your doctor.
Breastfeeding Consult your doctor
Ask your doctor before using it while breastfeeding.
Driving Caution
It may cause dizziness or drowsiness. Do not drive if you feel affected.
Kidney Caution
Use with caution in kidney disease. It should not be used in severe kidney disease.
Liver Caution
Use with caution in liver disease. It should not be used in severe liver disease.
If you miss a dose
If you miss a dose, take it when you remember. If it is nearly time for the next dose, skip the missed one. Do not take two doses together.
Quick tips
- Take it after food to protect your stomach.
- Do not take other painkillers that contain an NSAID or paracetamol at the same time unless your doctor says so.
- Drink enough water while taking it.
- Tell your doctor if you have had stomach ulcers, heart disease, high blood pressure or asthma.
Substitutes
Same salts in the same strength from other makers. Only switch brands on your doctor's or pharmacist's advice; our pharmacist checks every order against the prescription.
Fact box
- Chemical class
- Phenylacetic acid derivative (aceclofenac); para-aminophenol derivative (paracetamol); proteolytic enzyme (serratiopeptidase)
- Therapeutic class
- Pain relief / anti-inflammatory
- Action class
- NSAID + analgesic-antipyretic + proteolytic enzyme
- Habit forming
- No
- Prescription
- Required
Interactions with other medicines
Tell your doctor and pharmacist about every medicine, vitamin and herbal product you take.
| Medicine | What can happen |
|---|---|
| Other NSAIDs and aspirin | Higher risk of stomach bleeding and side effects |
| Blood thinners such as warfarin | Higher risk of bleeding |
| Blood pressure medicines and water pills (diuretics) | Their effect may be reduced and the kidneys may be strained |
| Lithium, methotrexate | Levels of these medicines may rise |
| Other medicines containing paracetamol | Risk of taking too much paracetamol |
This page is general information to help you understand your medicine. It is not a substitute for advice from your doctor or pharmacist. Do not start, stop or change a medicine on your own.
Written by the Asthra Health Care team from the approved prescribing information (Aceclofenac, paracetamol and serratiopeptidase prescribing information (CDSCO-approved labelling); NICE BNF: aceclofenac). Pharmacist review pending.