About Seroflo 250 Inhaler
Seroflo 250 Inhaler contains Salmeterol 25 mcg/dose + Fluticasone Propionate 250 mcg/dose. This is a combination inhaler used every day to control asthma and chronic obstructive pulmonary disease (COPD). Fluticasone is a steroid that reduces swelling in the airways, and salmeterol is a long-acting bronchodilator that keeps the airways open for about 12 hours. It is a 'preventer' and does not relieve a sudden attack — keep your quick-relief inhaler with you.
Uses of Seroflo 250 Inhaler
- Regular treatment of asthma
- Chronic obstructive pulmonary disease (COPD)
Benefits
In asthma
Used every day, it reduces airway swelling and keeps the airways open, so you have fewer symptoms and attacks and can be more active.
In COPD
It helps make breathing easier and can reduce flare-ups.
Side effects
Rinsing your mouth after each use helps prevent hoarseness and thrush. Talk to your doctor if side effects bother you.
Common
- Hoarse voice
- Sore throat
- Thrush (white patches) in the mouth or throat
- Headache
- Muscle cramps
Get medical help if you notice
- Sudden wheezing or tightness straight after using the inhaler — use your reliever and seek medical help at once
- Breathing that gets worse, or needing your reliever more often — contact your doctor promptly
- Fever, cough with more phlegm, or breathlessness (in COPD) — may be pneumonia; contact your doctor
- Fast or irregular heartbeat, chest pain — seek medical help
- Blurred vision or other eyesight changes — contact your doctor
How to use
Use it exactly as your doctor prescribed, usually twice a day. For the inhaler: shake it, breathe out fully, seal your lips around the mouthpiece, press once while breathing in slowly and deeply, then hold your breath for about 10 seconds. A spacer may help. For rotacaps: place one capsule in the device, pierce it, and breathe in quickly and deeply through the mouthpiece. Rinse your mouth with water and spit it out after each use.
How it works
Fluticasone is a corticosteroid that calms inflammation and swelling in the airways. Salmeterol relaxes the muscles around the airways for a long time, keeping them open.
Safety advice
Alcohol Safe
No interaction known.
Pregnancy Consult your doctor
Controlling asthma well in pregnancy is important. Use only if your doctor advises it.
Breastfeeding Consult your doctor
Ask your doctor before using it while breastfeeding.
Driving Safe
It is not expected to affect your ability to drive.
Kidney Consult your doctor
Tell your doctor if you have kidney disease.
Liver Consult your doctor
Tell your doctor if you have liver disease, as more of the steroid may reach the bloodstream.
If you miss a dose
If you miss a dose, take the next dose at the usual time. Do not take an extra dose to make up.
Quick tips
- Use it every day, even when you feel well.
- It does not stop a sudden attack — always carry your quick-relief inhaler.
- Rinse your mouth and spit after each use.
- Do not stop it suddenly; talk to your doctor first.
- Ask your pharmacist to check your inhaler technique.
Substitutes
Same salts in the same strength from other makers. Only switch brands on your doctor's or pharmacist's advice; our pharmacist checks every order against the prescription.
Same salts, other strengths or forms
Fact box
- Chemical class
- Synthetic corticosteroid (fluticasone); saligenin derivative (salmeterol)
- Therapeutic class
- Respiratory
- Action class
- Inhaled corticosteroid + long-acting beta-2 agonist (LABA)
- Habit forming
- No
- Prescription
- Required
Interactions with other medicines
Tell your doctor and pharmacist about every medicine, vitamin and herbal product you take.
| Medicine | What can happen |
|---|---|
| Ritonavir, cobicistat, ketoconazole and itraconazole | Raise levels of both medicines, increasing steroid and heart side effects; usually avoided |
| Beta-blockers, including eye drops (e.g. propranolol, timolol) | Can block salmeterol's effect and trigger wheezing |
| Water tablets (diuretics) and theophylline | May lower blood potassium |
| Other long-acting bronchodilator inhalers | Using two of the same type can cause side effects; do not combine unless told to |
This page is general information to help you understand your medicine. It is not a substitute for advice from your doctor or pharmacist. Do not start, stop or change a medicine on your own.
Written by the Asthra Health Care team from the approved prescribing information (Fluticasone propionate and salmeterol inhaler prescribing information (CDSCO-approved labelling); NICE BNF: fluticasone with salmeterol). Pharmacist review pending.