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Illustration of Prazosin 5 mg Tablet

Prazosin 5 mg Tablet

Prescription requiredSchedule HGenericBlood Pressure & Heart

Salt composition
Prazosin 5 mg (XL)
Form
Tablet
Storage
Store below 30°C, away from light and moisture, out of children's reach

Schedule H drug — Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.

About Prazosin 5 mg Tablet

Prazosin 5 mg Tablet contains Prazosin 5 mg (XL). Prazosin is an alpha-blocker used to treat high blood pressure. It can also ease urinary symptoms caused by an enlarged prostate. The extended-release tablet releases the medicine slowly through the day and must be swallowed whole.

Uses of Prazosin 5 mg Tablet

  • High blood pressure (hypertension)
  • Urinary symptoms of an enlarged prostate (benign prostatic hyperplasia), as advised by your doctor

Benefits

In high blood pressure

It relaxes blood vessels and lowers blood pressure, which reduces the risk of heart attack, stroke and kidney damage.

In an enlarged prostate

It relaxes muscles around the bladder outlet, which can make it easier to pass urine.

Side effects

Dizziness on standing is most common at the start. Get up slowly from sitting or lying down.

Common

  • Dizziness, especially when standing up
  • Drowsiness
  • Headache
  • Weakness or tiredness
  • Palpitations
  • Blocked nose

Get medical help if you notice

  • Fainting, especially after the first dose or a dose increase — lie down and contact your doctor
  • A painful erection lasting more than 4 hours — seek emergency care
  • Chest pain or a fast, irregular heartbeat — seek medical help
  • Allergic reaction: rash, swelling of the face or lips, difficulty breathing — seek emergency care

How to use

Take it exactly as your doctor prescribed. Swallow the extended-release tablet whole with water; do not crush, chew or break it. Your doctor may advise taking the first dose at bedtime.

How it works

It blocks alpha-1 receptors in the walls of blood vessels and in the prostate and bladder neck. This relaxes the muscle, so blood vessels widen and urine flows more easily.

Safety advice

Alcohol Caution

Alcohol can increase dizziness and the drop in blood pressure. Limit alcohol.

Pregnancy Consult your doctor

Use only if your doctor advises it. Tell your doctor if you are pregnant or planning a pregnancy.

Breastfeeding Consult your doctor

Small amounts pass into breast milk. Ask your doctor before using it while breastfeeding.

Driving Caution

It can cause dizziness or drowsiness, especially at the start. Do not drive until you know how it affects you.

Kidney Caution

Your doctor may start with a lower dose if you have kidney disease.

Liver Caution

Your doctor may start with a lower dose if you have liver disease.

If you miss a dose

If you miss a dose, take it when you remember the same day. If it is nearly time for the next dose, skip the missed one. Do not take two doses together.

Quick tips

  • Get up slowly from sitting or lying down to avoid dizziness.
  • Swallow the tablet whole; you may see the empty tablet shell in your stool, which is normal for some extended-release tablets.
  • Tell your eye surgeon you take it if you are having cataract surgery.
  • Do not stop it suddenly without talking to your doctor.

Substitutes

Same salts in the same strength from other makers. Only switch brands on your doctor's or pharmacist's advice; our pharmacist checks every order against the prescription.

Fact box

Chemical class
Quinazoline derivative
Therapeutic class
Cardiovascular / antihypertensive
Action class
Alpha-1 adrenergic blocker
Habit forming
No
Prescription
Required

Interactions with other medicines

Tell your doctor and pharmacist about every medicine, vitamin and herbal product you take.

MedicineWhat can happen
Sildenafil, tadalafil and similar erectile dysfunction medicinesCan lower blood pressure too much
Other blood pressure medicines and water tablets (diuretics)Can add to the lowering of blood pressure
Beta-blockersHigher risk of fainting after the first dose
Alcohol and sedativesCan add to dizziness and drowsiness

This page is general information to help you understand your medicine. It is not a substitute for advice from your doctor or pharmacist. Do not start, stop or change a medicine on your own.

Written by the Asthra Health Care team from the approved prescribing information (Prazosin prescribing information (CDSCO-approved labelling); EMC SmPC: prazosin; NICE BNF: prazosin). Pharmacist review pending.

Questions

Frequently asked

Why should the first dose be at bedtime?

The first dose can cause a sudden drop in blood pressure. Taking it at bedtime lowers the chance of fainting.

Can I crush the tablet?

No. Crushing an extended-release tablet can release too much medicine at once.

Will it treat my prostate enlargement?

It eases urinary symptoms but does not shrink the prostate. Your doctor will review your symptoms.

Can I stop it if I feel fine?

Do not stop it without talking to your doctor.

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