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Illustration of Neo-Mercazole 5 Tablet

Neo-Mercazole 5 Tablet

Prescription requiredSchedule HThyroid

Salt composition
Carbimazole 5 mg
Form
Tablet
Storage
Store below 30°C, away from light and moisture, out of children's reach

Schedule H drug — Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.

About Neo-Mercazole 5 Tablet

Neo-Mercazole 5 Tablet contains Carbimazole 5 mg. Carbimazole is an antithyroid medicine used to treat an overactive thyroid (hyperthyroidism). It reduces the amount of thyroid hormone the gland makes. It is taken by mouth, and your doctor will adjust treatment based on regular blood tests.

Uses of Neo-Mercazole 5 Tablet

  • Overactive thyroid (hyperthyroidism), including Graves' disease
  • To prepare the thyroid before surgery or radioactive iodine treatment

Benefits

In overactive thyroid

It lowers thyroid hormone levels, which eases symptoms such as a fast heartbeat, weight loss, shaking, sweating and anxiety. Improvement usually takes a few weeks.

Side effects

A rare but serious side effect is a fall in white blood cells. Always report a sore throat or fever to your doctor straight away.

Common

  • Rash or itching
  • Nausea
  • Headache
  • Joint pain
  • Mild stomach upset

Get medical help if you notice

  • Sore throat, mouth ulcers, fever or any sign of infection (possible low white blood cells) — stop and see your doctor straight away for a blood test
  • Unusual bruising or bleeding — contact your doctor straight away
  • Yellow eyes or skin, dark urine or pale stools (possible liver problems) — stop and contact your doctor
  • Severe stomach pain spreading to the back (possible pancreatitis) — seek medical help
  • Allergic reaction: swelling of the face or lips, difficulty breathing — seek emergency care

How to use

Take it exactly as your doctor prescribed. Swallow the tablet with water. Go for blood tests as advised so the dose can be adjusted.

How it works

In the body it is changed into methimazole, which blocks an enzyme the thyroid needs to make thyroid hormones.

Safety advice

Alcohol Caution

No direct interaction is known. As the medicine can rarely affect the liver, keep alcohol to a minimum.

Pregnancy Consult your doctor

It can cross the placenta and may cause birth defects, especially in early pregnancy. Use reliable contraception and tell your doctor straight away if you are pregnant or planning a pregnancy.

Breastfeeding Consult your doctor

It passes into breast milk. Ask your doctor; the baby may need monitoring.

Driving Caution

It is not known to affect driving, but do not drive if you feel dizzy or unwell.

Kidney Caution

Tell your doctor if you have kidney disease; the dose may need adjusting.

Liver Caution

Use with caution in liver disease. It must not be used in severe liver disease.

If you miss a dose

If you miss a dose, take it when you remember. If it is nearly time for the next dose, skip the missed one. Do not take two doses together.

Quick tips

  • Report a sore throat, fever or mouth ulcers to your doctor straight away.
  • Go for regular thyroid blood tests.
  • Use reliable contraception if you could become pregnant.
  • Do not stop it without talking to your doctor.

Substitutes

Same salts in the same strength from other makers. Only switch brands on your doctor's or pharmacist's advice; our pharmacist checks every order against the prescription.

Fact box

Chemical class
Imidazole derivative (thionamide)
Therapeutic class
Hormone / thyroid
Action class
Antithyroid agent
Habit forming
No
Prescription
Required

Interactions with other medicines

Tell your doctor and pharmacist about every medicine, vitamin and herbal product you take.

MedicineWhat can happen
Blood thinners such as warfarinTheir effect may change as thyroid levels change; extra blood tests may be needed
TheophyllineIts levels may change as thyroid levels change
DigoxinIts levels may rise as thyroid levels return to normal
Prednisolone and erythromycinTheir effects may change as thyroid levels change

This page is general information to help you understand your medicine. It is not a substitute for advice from your doctor or pharmacist. Do not start, stop or change a medicine on your own.

Written by the Asthra Health Care team from the approved prescribing information (Carbimazole prescribing information (CDSCO-approved labelling); EMC SmPC: carbimazole; NICE BNF: carbimazole). Pharmacist review pending.

Questions

Frequently asked

How long before I feel better?

Most people start to feel better after a few weeks. Thyroid levels are checked regularly.

Why is a sore throat important?

Rarely, this medicine lowers white blood cells, which fight infection. A sore throat or fever can be the first sign.

How long will I need it?

Treatment often lasts many months. Your doctor will decide based on your blood tests.

Can I become underactive on it?

Yes, if the dose is too high. Tell your doctor if you feel tired, cold or gain weight.

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