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Illustration of Levothyroxine 50 mcg Tablet

Levothyroxine 50 mcg Tablet

Prescription requiredSchedule HGenericThyroid

Salt composition
Levothyroxine 50 mcg
Form
Tablet
Storage
Store below 30°C, away from light and moisture, out of children's reach

Schedule H drug — Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.

About Levothyroxine 50 mcg Tablet

Levothyroxine 50 mcg Tablet contains Levothyroxine 50 mcg. Levothyroxine is a man-made form of thyroxine, a hormone normally made by the thyroid gland. It is used to replace the hormone when the thyroid does not make enough (hypothyroidism). It is usually taken once a day on an empty stomach, and most people need it long term. Your doctor will adjust the dose using blood tests.

Uses of Levothyroxine 50 mcg Tablet

  • Hypothyroidism (underactive thyroid)
  • Replacement after thyroid surgery or treatment
  • Some types of goitre and thyroid cancer, as advised by the specialist

Benefits

In hypothyroidism

It replaces the missing thyroid hormone, which helps with tiredness, weight gain, feeling cold, constipation and low mood caused by an underactive thyroid. It may take a few weeks to feel the full benefit.

Side effects

Most side effects are signs that the dose needs adjusting. Do not change the dose yourself; talk to your doctor.

Common

  • Usually few side effects at the right dose
  • Fast heartbeat or palpitations (if the dose is too high)
  • Feeling nervous, shaky or unable to sleep (if the dose is too high)
  • Sweating or feeling hot
  • Temporary hair thinning in the first months

Get medical help if you notice

  • Chest pain, fast or irregular heartbeat — seek medical help straight away
  • Severe headache, tremor, weight loss, diarrhoea or heat intolerance — may mean the dose is too high; contact your doctor
  • Allergic reaction: rash, swelling of the face or throat — seek emergency care

How to use

Take it exactly as your doctor prescribed, once a day on an empty stomach, usually 30 to 60 minutes before breakfast. Swallow the tablet with a glass of water. Take it the same way every day.

How it works

Levothyroxine is converted in the body into the active thyroid hormone. This hormone controls how fast the body uses energy (metabolism), restoring normal hormone levels.

Safety advice

Alcohol Caution

No direct interaction is known. Keep alcohol within safe limits.

Pregnancy Safe

It is important to keep taking it in pregnancy. The dose often needs to go up, so tell your doctor as soon as you know you are pregnant.

Breastfeeding Safe

Only tiny amounts pass into breast milk, and this is not expected to harm the baby. Keep taking it as prescribed.

Driving Safe

It is not expected to affect your ability to drive.

Kidney Consult your doctor

Tell your doctor if you have kidney disease.

Liver Consult your doctor

Tell your doctor if you have liver disease.

If you miss a dose

If you miss a dose, take it as soon as you remember. If it is nearly time for the next dose, skip the missed one. Do not take two doses together.

Quick tips

  • Take it on an empty stomach, at the same time each day.
  • Keep a gap of at least 4 hours between this medicine and calcium, iron or antacid products.
  • Go for thyroid blood tests as your doctor advises.
  • Do not use it for weight loss — it can be dangerous.
  • Stick to the same brand if possible; tell your doctor if your brand changes.

Substitutes

Same salts in the same strength from other makers. Only switch brands on your doctor's or pharmacist's advice; our pharmacist checks every order against the prescription.

Same salts, other strengths or forms

Fact box

Chemical class
Synthetic thyroid hormone (T4)
Therapeutic class
Hormone / thyroid
Action class
Thyroid hormone replacement
Habit forming
No
Prescription
Required

Interactions with other medicines

Tell your doctor and pharmacist about every medicine, vitamin and herbal product you take.

MedicineWhat can happen
Calcium, iron, antacids and some cholesterol-binding medicinesReduce absorption of levothyroxine; keep at least 4 hours apart
WarfarinIts blood-thinning effect may increase
Insulin and other diabetes medicinesTheir dose may need adjusting when thyroid treatment starts or changes
Carbamazepine, phenytoin and rifampicinMay reduce the effect of levothyroxine
Estrogen-containing medicinesMay increase how much levothyroxine you need

This page is general information to help you understand your medicine. It is not a substitute for advice from your doctor or pharmacist. Do not start, stop or change a medicine on your own.

Written by the Asthra Health Care team from the approved prescribing information (Levothyroxine prescribing information (CDSCO-approved labelling); NICE BNF: levothyroxine sodium). Pharmacist review pending.

Questions

Frequently asked

Do I have to take it for life?

Many people with hypothyroidism need it long term. Your doctor will tell you how long you need it.

Why must I take it on an empty stomach?

Food, coffee and some supplements reduce how much of the medicine is absorbed.

How soon will I feel better?

Some people feel better within a couple of weeks, but it can take several weeks. Your doctor will check your blood tests and adjust the dose.

Can I take it during pregnancy?

Yes. Do not stop it. Tell your doctor straight away, as your dose often needs to be increased.

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