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Illustration of Levipil 500 Tablet

Levipil 500 Tablet

Prescription requiredSchedule HNeurology

Manufacturer
Sun Pharmaceutical Industries Ltd
Salt composition
Levetiracetam 500 mg
Form
Tablet
Storage
Store below 30°C, away from light and moisture, out of children's reach

Schedule H drug — Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.

About Levipil 500 Tablet

Levipil 500 Tablet contains Levetiracetam 500 mg. This is an anti-epileptic medicine used to control seizures (fits) in epilepsy, on its own or with other seizure medicines. It is taken every day to prevent seizures. Do not stop it suddenly, as this can bring on seizures.

Uses of Levipil 500 Tablet

  • Partial-onset (focal) seizures, with or without spreading
  • Myoclonic seizures (with other medicines)
  • Generalised tonic-clonic seizures (with other medicines)

Benefits

In epilepsy

Taken regularly, it can reduce how often seizures happen, and in some people stop them altogether. This can help you live more safely and confidently. It controls seizures but does not cure epilepsy.

Side effects

Most side effects are mild and settle as your body gets used to the medicine. Talk to your doctor if any of them bother you or do not go away.

Common

  • Drowsiness
  • Tiredness
  • Dizziness
  • Headache
  • Irritability or mood changes
  • Common cold-like symptoms

Get medical help if you notice

  • New or worsening low mood, anxiety, agitation, unusual behaviour or thoughts of self-harm — contact your doctor straight away
  • Seizures that become more frequent or longer — get medical help
  • Severe skin rash with blistering, peeling, mouth ulcers or fever — stop and get medical help straight away
  • Allergic reaction: rash, itching, swelling of the face, lips or throat, or difficulty breathing — seek emergency care

How to use

Take it exactly as your doctor prescribed, usually twice a day at about the same times. Swallow the tablet whole with water; it can be taken with or without food. Do not stop it suddenly.

How it works

It binds to a protein in nerve cells (SV2A) that controls the release of chemical messengers. This helps calm excess electrical activity in the brain that leads to seizures.

Safety advice

Alcohol Unsafe

Avoid alcohol. It can increase drowsiness and may make seizures more likely.

Pregnancy Consult your doctor

Talk to your doctor before planning a pregnancy. Do not stop taking it on your own if you become pregnant, as seizures can harm you and the baby.

Breastfeeding Consult your doctor

It passes into breast milk. Ask your doctor before breastfeeding.

Driving Caution

It can cause drowsiness. Follow your doctor's advice and local rules on driving with epilepsy.

Kidney Caution

Your doctor will adjust the dose if you have kidney disease.

Liver Caution

Your doctor may adjust the dose in severe liver disease.

If you miss a dose

If you miss a dose, take it when you remember. If it is nearly time for the next dose, skip the missed one. Do not take two doses together.

Quick tips

  • Do not stop taking it suddenly — this can trigger seizures. Your doctor will reduce the dose slowly if needed.
  • Take it at the same times each day.
  • Tell your doctor about any change in mood or behaviour.
  • Keep a record of any seizures to share with your doctor.

Substitutes

Same salts in the same strength from other makers. Only switch brands on your doctor's or pharmacist's advice; our pharmacist checks every order against the prescription.

Fact box

Chemical class
Pyrrolidine derivative
Therapeutic class
Neurology
Action class
Anti-epileptic (SV2A ligand)
Habit forming
No
Prescription
Required

Interactions with other medicines

Tell your doctor and pharmacist about every medicine, vitamin and herbal product you take.

MedicineWhat can happen
Alcohol, sedatives, sleeping pillsIncreased drowsiness
MethotrexateLevels of methotrexate may rise
Macrogol laxativesMay reduce absorption if taken within 1 hour

This page is general information to help you understand your medicine. It is not a substitute for advice from your doctor or pharmacist. Do not start, stop or change a medicine on your own.

Written by the Asthra Health Care team from the approved prescribing information (Levetiracetam prescribing information (CDSCO-approved labelling); NICE BNF: levetiracetam). Pharmacist review pending.

Questions

Frequently asked

How long will I need to take it?

Often for years. Your doctor will decide if and when it can be slowly stopped.

Does it interact with the contraceptive pill?

It is not known to make the pill less effective, but tell your doctor about all medicines you take.

Why do I feel irritable?

Mood changes can happen with this medicine. Tell your doctor, especially if they are severe.

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