About Itraconazole 100 mg Capsule
Itraconazole 100 mg Capsule contains Itraconazole 100 mg. This is an antifungal medicine used to treat fungal infections of the skin, nails, mouth, vagina and some internal organs. It is taken as capsules, usually after a full meal. It interacts with many other medicines, so tell your doctor and pharmacist everything you take.
Uses of Itraconazole 100 mg Capsule
- Fungal skin infections such as ringworm (tinea)
- Fungal nail infections
- Vaginal and mouth thrush
- Some serious internal fungal infections (as decided by a doctor)
Benefits
In fungal infections
It stops the fungus from growing so the infection can clear. Skin may improve within weeks, but nail infections take months because the nail has to grow out. Complete the course your doctor prescribes.
Side effects
Most side effects are mild and settle as your body gets used to the medicine. Talk to your doctor if any of them bother you or do not go away.
Common
- Stomach pain
- Nausea
- Headache
- Rash
- Diarrhoea
Get medical help if you notice
- Yellowing of the skin or eyes, dark urine, pale stools, loss of appetite or unusual tiredness — stop and get medical help
- Breathlessness, swelling of the legs or ankles or unusual weight gain (possible heart failure) — stop and contact your doctor
- Numbness or tingling in the hands or feet, or hearing loss — contact your doctor
- Severe skin rash with blistering or peeling — stop and get medical help
- Allergic reaction: rash, itching, swelling of the face, lips or throat, or difficulty breathing — seek emergency care
How to use
Take it exactly as your doctor prescribed. Swallow the capsules whole straight after a full meal, which helps the body absorb them. Complete the full course, even if the infection looks better.
How it works
It blocks the fungus from making ergosterol, an essential part of its cell membrane. Without it, the fungus cannot grow.
Safety advice
Alcohol Caution
Avoid alcohol or keep it to a minimum. Both alcohol and this medicine can affect the liver.
Pregnancy Unsafe
It should not be used in pregnancy except for serious infections when a doctor decides it is essential. Use reliable contraception during treatment and until your next period after finishing.
Breastfeeding Consult your doctor
It passes into breast milk. Ask your doctor before using it while breastfeeding.
Driving Caution
It may cause dizziness or blurred vision. Do not drive if you feel affected.
Kidney Caution
Tell your doctor if you have kidney disease; the medicine may need monitoring.
Liver Caution
Use with caution in liver disease. Your doctor may check your liver with blood tests.
If you miss a dose
If you miss a dose, take it with your next meal if it is soon after. If it is nearly time for the next dose, skip the missed one. Do not take two doses together.
Quick tips
- Take it straight after a full meal.
- Tell your doctor and pharmacist about all other medicines you take — many cannot be taken with it.
- Do not take antacids or acid-reducing medicines close to your dose unless your doctor says so.
- Tell your doctor if you have heart failure or liver disease.
- Complete the full course.
Substitutes
Same salts in the same strength from other makers. Only switch brands on your doctor's or pharmacist's advice; our pharmacist checks every order against the prescription.
Same salts, other strengths or forms
Fact box
- Chemical class
- Triazole
- Therapeutic class
- Anti-infective / antifungal
- Action class
- Azole antifungal (ergosterol synthesis inhibitor)
- Habit forming
- No
- Prescription
- Required
Interactions with other medicines
Tell your doctor and pharmacist about every medicine, vitamin and herbal product you take.
| Medicine | What can happen |
|---|---|
| Simvastatin, lovastatin | Must not be taken together — high risk of muscle damage |
| Some heart rhythm medicines and certain other drugs (such as domperidone) | Can cause dangerous heart rhythm problems |
| Midazolam and triazolam (by mouth) | Increased and longer sedation; must not be taken together |
| Antacids and acid-reducing medicines | Reduce absorption of itraconazole capsules |
| Rifampicin, carbamazepine, phenytoin | Can make itraconazole much less effective |
This page is general information to help you understand your medicine. It is not a substitute for advice from your doctor or pharmacist. Do not start, stop or change a medicine on your own.
Written by the Asthra Health Care team from the approved prescribing information (Itraconazole capsules prescribing information (CDSCO-approved labelling); US FDA boxed warning for itraconazole (heart failure and drug interactions)). Pharmacist review pending.