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Illustration of Domperidone 10 mg Tablet

Domperidone 10 mg Tablet

Prescription requiredSchedule HGenericAcidity & Digestion

Salt composition
Domperidone 10 mg
Form
Tablet
Storage
Store below 30°C, away from light and moisture, out of children's reach

Schedule H drug — Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only.

About Domperidone 10 mg Tablet

Domperidone 10 mg Tablet contains Domperidone 10 mg. This medicine is used to relieve nausea and vomiting and a feeling of fullness or bloating after meals. It helps the stomach empty faster. It is meant for short-term use, at the lowest dose that works, because it can rarely affect heart rhythm.

Uses of Domperidone 10 mg Tablet

  • Nausea and vomiting
  • Bloating, fullness and discomfort after meals (as decided by a doctor)

Benefits

In nausea and vomiting

It helps settle the stomach so you can keep food and fluids down. It eases the symptom; the cause should be checked by a doctor if it does not settle.

Side effects

Most side effects are mild and settle as your body gets used to the medicine. Talk to your doctor if any of them bother you or do not go away.

Common

  • Dry mouth
  • Headache
  • Diarrhoea
  • Drowsiness

Get medical help if you notice

  • Fast, irregular or pounding heartbeat, fainting or fits — stop and get medical help straight away
  • Breast swelling or milk discharge, or changes in periods — tell your doctor
  • Uncontrolled movements of the face, eyes, neck or tongue — contact your doctor
  • Allergic reaction: rash, itching, swelling of the face, lips or throat, or difficulty breathing — seek emergency care

How to use

Take it exactly as your doctor prescribed, usually 15 to 30 minutes before meals. Swallow the tablet with water. Do not take it for longer than your doctor advises, usually no more than about a week.

How it works

It blocks dopamine in the gut and in the part of the brain that triggers vomiting. This reduces nausea and helps the stomach empty.

Safety advice

Alcohol Caution

Avoid alcohol or keep it to a minimum. It can irritate the stomach and make nausea worse.

Pregnancy Consult your doctor

Use only if your doctor advises it. Tell your doctor if you are pregnant or planning a pregnancy.

Breastfeeding Consult your doctor

Small amounts pass into breast milk. Ask your doctor before using it while breastfeeding.

Driving Caution

It may cause drowsiness or dizziness in some people. Do not drive if you feel affected.

Kidney Caution

Tell your doctor if you have severe kidney disease; you may need to take it less often.

Liver Unsafe

It must not be used in moderate or severe liver disease.

If you miss a dose

If you miss a dose, take it when you remember. If it is nearly time for the next dose, skip the missed one. Do not take two doses together.

Quick tips

  • Take it before meals.
  • Use it for the shortest time your doctor advises.
  • Tell your doctor if you have a heart condition or take other medicines that affect heart rhythm.
  • If vomiting is severe or you cannot keep fluids down, see a doctor.

Substitutes

Same salts in the same strength from other makers. Only switch brands on your doctor's or pharmacist's advice; our pharmacist checks every order against the prescription.

Fact box

Chemical class
Benzimidazole derivative
Therapeutic class
Gastrointestinal
Action class
Dopamine D2 antagonist (prokinetic and antiemetic)
Habit forming
No
Prescription
Required

Interactions with other medicines

Tell your doctor and pharmacist about every medicine, vitamin and herbal product you take.

MedicineWhat can happen
Ketoconazole, itraconazole, clarithromycin, erythromycinRaise domperidone levels and the risk of heart rhythm problems
Other medicines that affect heart rhythmHigher risk of heart rhythm problems
Antacids or acid-reducing medicinesMay reduce absorption; take domperidone before them

This page is general information to help you understand your medicine. It is not a substitute for advice from your doctor or pharmacist. Do not start, stop or change a medicine on your own.

Written by the Asthra Health Care team from the approved prescribing information (Domperidone prescribing information (CDSCO-approved labelling); EMA review of domperidone-containing medicines, 2014). Pharmacist review pending.

Questions

Frequently asked

How fast does it work?

It usually starts to help within an hour.

Can children take it?

Children's doses are different and it is used only in some situations. Use only what a doctor has prescribed for the child.

Why is it only for short-term use?

Higher doses and longer use slightly increase the risk of heart rhythm problems.

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